nPOD - Type 1 Diabetes

NPOD. JDRF is committed to finding a method for preventing or permanently reversing type 1 diabetes; an effort that would undoubtedly...

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Npod.org news digest

  • 1 year

    Unbiased single cell resolution spatial proteomics: defining the antigenic lands...

    Diabetes is a complex metabolic disease in which patients experience high blood glucose levels leading to a plethora of symptoms and long-term complications. In type 1 diabetes (T1D), this happens likely due to an autoimmune reaction targeting the insulin...

  • 1 year

    Targeting the innate immune system to discover new therapeutic pathways for the ...

    Type 1 diabetes (T1D) is an autoimmune disease, where immune cells (T cells) of the body attack and destroy the insulin-producing beta cells. T1D is, if left untreated, a devastating and life-threatening disease and despite intensive research in the...

  • 1 year

    CD6 and its ligands in Type 1 Diabetes

    Type 1 diabetes mellitus (T1D) results from the autoimmune attack of pancreatic β-cells, resulting in a loss of functional β-cell mass. The CD6 molecule is a membrane glycoprotein predominantly expressed on T cells and is implicated in lymphocyte adhesion...

  • 1 year

    IAPP and innate immunity in T1D

    Islet amyloid polypeptide (IAPP) is a beta-cell peptide hormone that forms toxic and pro-inflammatory aggregates in pathological states, including T2D and islet transplants. Recent evidence suggests the presence of fibrillar aggregates of IAPP (islet...

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Updated: January 12, 2022
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