Duke Clinical Research Institute - DCRI

November 12, 2018 – A DCRI substudy identified proteins that may differentiate diastolic dysfunction in HIV patients from non-HIV individuals.
As antiretroviral therapy has transformed HIV from a potentially fatal disease to a chronic one, persons living with HIV (PLHIV) may develop more cardiovascular risk factors and CV-related morbidity and mortality, even with viral suppression, than those...

November 11, 2018 – The award is given to physicians who demonstrate excellence in mentoring young academic clinicians.
The American Heart Association(AHA) has awarded DCRI founder and former FDA Commissioner Robert M. Califf, MD, the 2018 Eugene Braunwald Award for Academic Mentoring. The award, which is given to physicians who demonstrate a consistent track record of...

November 11, 2018 – A DCRI analysis of patient data from the PALM Registry examines possible reasons for the treatment gap.
While the safety and efficacy of statin therapy for the prevention of atherosclerotic cardiovascular disease is well-established, female patients have historically received less aggressive lipid management than males, according to the DCRI’s Michael...

November 11, 2018 –A new therapy could lead to improved outcomes for patients with acute decompensated heart failure.
New study results support the safety of in-hospital initiation of sacubitril-valsartan for heart failure with reduced ejection fraction (HFrEF) and may point to improved short-term clinical outcomes for patients who receive this treatment....