Learning from and about cancer (chronic lymphocytic leukemia or CLL) b...

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Bkoffman.blogspot.com news digest

  • 5 years

    ASH 2017: Dr. Thomas Kipps on the ROR1 Antibody, Cirmtuzumab

    At ASH 2017 held in December in Atlanta, Dr. Thomas Kipps from the Moore Cancer Center at UCSD in San Diego, CA talked about an exciting new target for very specifically killing off chronic lymphocytic leukemia cells while sparing normal cells, including...

  • 5 years

    ASH 2017: Dr. Adrian Wiestner on Resistance Mechanism in CLL (chronic lymphocyti...

    I had the opportunity to interview Dr. Adrian Wiestner from the National Institutes of Health at ASH 2017 in Atlanta GA about his and other researchers work on how CLL cells become resistant to ibrutinib and venetoclax.
    Take Away Points:
    Ibrutinib works so well in chronic lymphocytic leukemia because it blocks the B-cell receptors (BCR) by binding to Bruton’s Tyrosine Kinase (BTK). This blocking of the BCR leads to cell death....

  • 5 years

    He Did It

    Hi,
    Stan Kurtz and his team, with help from so many of you, Did it. He swam the Catalina channel and raised his goal of over $25.000 for the CLL Society! Thanks to all who gave, but it's not too late to share in there joy. Consider a tax deductible (in the...

  • 5 years

    10 years ago today I received my Transplant for my CLL (chronic lymphocytic leuk...

    July 1, 2008, Canada Day, was my first Day Zero- my first shot at a cure when after conditioning chemo-immunotherapy of FCR, I received my hematopoietic stem cells from an unrelated donor who I later discovered was from Israel.
    The allogeneic HSCT didn't work- though the chemo gave me a short but deep remission. I never engrafted, and when I quickly relapse, my cancer was meaner, a 17p deletion had shown up and my chronic lymphocytic leukemia required a new approach....

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Created: July 31, 2000

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